May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Central Retinal Artery and Vein Collapse Pressure in Giant Cell Arteritis versus Nonarteritic Anterior Ischemic Optic Neuropathy
Author Affiliations & Notes
  • J. B. Jonas
    Ophthalmology, Fac Clin Med Mannheim-Heidelberg, Mannheim, Germany
  • B. Harder
    Ophthalmology, Fac Clin Med Mannheim-Heidelberg, Mannheim, Germany
  • B. Harder
    Ophthalmology, Fac Clin Med Mannheim-Heidelberg, Mannheim, Germany
  • Footnotes
    Commercial Relationships J.B. Jonas, None; B. Harder, None; B. Harder, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4414. doi:
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      J. B. Jonas, B. Harder, B. Harder; Central Retinal Artery and Vein Collapse Pressure in Giant Cell Arteritis versus Nonarteritic Anterior Ischemic Optic Neuropathy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4414.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To measure the central retinal artery (CRA) and vein (CRV) collapse pressure in anterior ischemic optic neuropathy.

Methods:: Using a Goldmann contact lens associated ophthalmodynamometer, the diastolic collapse pressure of the CRA and CRV were measured in 6 patients (8 eyes) with giant cell arteritis induced anterior ischemic optic neuropathy (GC-AION) and in 10 patients (12 eyes) with acute non-arteritic anterior ischemic optic neuropathy (NAION).

Results:: CRA collapse pressure was significantly (P=0.001; 95% confidence interval (CI):-68.7,-20.0) lower in the GC-AION group (52.7ѱ24.6 arbitrary units) than in the NAION group (97.0ѱ25.8 arbitrary units). CRV collapse pressure did not vary significantly (P=0.47).

Conclusions:: As measured by ophthalmodynamometry, CRA pressure is significantly lower in GC-AION than in NAION. CRV pressure does not vary markedly. These finding may be helpful for the clinical differentiation between GC-AION and NAION, and may give hints for the pathogenesis.

Keywords: optic nerve • optic disc • neuro-ophthalmology: diagnosis 
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