May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Autofluorescence in Adult-Onset Foveomacular Vitelliform Dystrophy
Author Affiliations & Notes
  • M. B. Parodi
    Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste, Trieste, Italy
  • P. Iacono
    Fondazione G.B. Bietti-IRCCS, G. B. Bietti Eye Foundation, Roma, Italy
  • A. Fachin
    Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste, Trieste, Italy
  • M. Pinto
    Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste, Trieste, Italy
  • M. Pedio
    Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste, Trieste, Italy
  • G. Ravalico
    Clinica Oculistica, Azienda Ospedaliero-Universitaria di Trieste, Trieste, Italy
  • Footnotes
    Commercial Relationships M.B. Parodi, None; P. Iacono, None; A. Fachin, None; M. Pinto, None; M. Pedio, None; G. Ravalico, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4512. doi:
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    • Get Citation

      M. B. Parodi, P. Iacono, A. Fachin, M. Pinto, M. Pedio, G. Ravalico; Autofluorescence in Adult-Onset Foveomacular Vitelliform Dystrophy. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4512.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: Yo describe fundus autofluorescence (FAF) characteristics of Adult-onset Foveomacular Vitelliform Dystrophy (AOFVD) and to find a correlation with the functional responses.

Methods:: Patients affected by AOFVD underwent a complete ophthalmologic examination, including ETDRS visual acuity, blue-light autofluorescence (BL-FAF) and near-infrared autofluorescence (NIR-FAF) performed using the HRA confocal scanning laser ophthalmoscope, and microperimetry (MP-1 Microperimeter, Nidek).

Results:: 15 patients affected by AOFVD were enrolled. Three different patterns were identified on BL-FAF and 2 on NIR-AF. Patchy pattern both on BL-FAF and on NIR-FAF reveal the worst functional response, showing lowest visual acuity and retinal sensitivity values.

Conclusions:: A functional correlate with visual acuity and retinal sensitivity, measured by means of microperimetry, can be found. Longitudinal studies investigating the natural course of FAF patterns of AOFVD may be useful both to identify genetic influence and prognostic factors, and to determine specific clinical and functional correlates.

Keywords: retinal degenerations: hereditary • retinal pigment epithelium • clinical (human) or epidemiologic studies: systems/equipment/techniques 
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