May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
A Cross-Sectional Analysis of Cases Requiring Resuturing Following Penetrating Keratoplasty (PK)
Author Affiliations & Notes
  • V. Jeganathan
    Royal Victorian Eye and Ear Hospital, Melbourne, Australia
  • E. Lamoureux
    Centre for Eye Research of Australia, University of Melbourne, Australia
  • H. Taylor
    Royal Victorian Eye and Ear Hospital, Melbourne, Australia
    Centre for Eye Research of Australia, University of Melbourne, Australia
  • R. B. Vajpayee
    Royal Victorian Eye and Ear Hospital, Melbourne, Australia
    Centre for Eye Research of Australia, University of Melbourne, Australia
  • Footnotes
    Commercial Relationships V. Jeganathan, None; E. Lamoureux, None; H. Taylor, None; R.B. Vajpayee, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4696. doi:
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    • Get Citation

      V. Jeganathan, E. Lamoureux, H. Taylor, R. B. Vajpayee; A Cross-Sectional Analysis of Cases Requiring Resuturing Following Penetrating Keratoplasty (PK). Invest. Ophthalmol. Vis. Sci. 2007;48(13):4696.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To study the clinical profile of cases requiring resuturing following penetrating keratoplasty (PK) at a major tertiary care eye hospital.

Methods:: The medical records of 947 consecutive patients attending a public eye hospital (Melbourne, Australia) who underwent PK between 01/07/96 and 30/06/06 were reviewed retrospectively. Clinical parameters like the indication for PK, suturing techniques, causes of resuturing and visual outcome were studied. Indications for resuturing were classified as loose suture, wound dehiscence, high astigmatism, suture infections and additional sutures.

Results:: Of the 947 eyes that underwent PK, 51 (5.4%) returned for resuturing. Overall, the most common indication for PK in the resutured eyes was keratoconus (66.7%) followed by corneal endothelial decompensation (17.6%) and microbial keratitis (7.8%) (Χ2(df) 32.2(3); p=0.001). Indication-wise analysis tended to show that more eyes with microbial keratitis (12.1%) and keratoconus (10.4%) required resuturing of the graft, versus corneal endothelial decompensation (2.2%), though this difference only approached statistical significance (Χ2(df) 3.1(1), p=0.08). Wound dehiscence (51%), loose sutures (25.5%) and unsatisfactory closure of the host graft junction (9.8%) were the main indications for resuturing. Resuturing did not result in a significant visual loss (t-test; p>0.05).

Conclusions:: Corneal grafts done for microbial keratitis and keratoconus may require resuturing more commonly, and wound dehiscence appears to be the major indication for resuturing.

Keywords: cornea: clinical science • clinical (human) or epidemiologic studies: outcomes/complications • transplantation 
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