May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Descemet’s Stripping Endothelial Keratoplasty versus Penetrating Keratoplasty: Post-Operative Visual and Refractive Outcomes
Author Affiliations & Notes
  • F. McDonald
    Ophthalmology, University of Mississippi Medical Center, Jackson, Mississippi
  • B. Huang
    Ophthalmology, University of Mississippi Medical Center, Jackson, Mississippi
  • C. McCaa
    Ophthalmology, University of Mississippi Medical Center, Jackson, Mississippi
  • L. Wigington
    Ophthalmology, University of Mississippi Medical Center, Jackson, Mississippi
  • Footnotes
    Commercial Relationships F. McDonald, None; B. Huang, None; C. McCaa, None; L. Wigington, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 4703. doi:
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      F. McDonald, B. Huang, C. McCaa, L. Wigington; Descemet’s Stripping Endothelial Keratoplasty versus Penetrating Keratoplasty: Post-Operative Visual and Refractive Outcomes. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4703.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To compare pre-operative and post-operative visual acuity and refractive outcome following Descemet’s stripping endothelial keratoplasty (DSEK) and penetrating keratoplasty (PKP) in the treatment of corneal endothelial dysfunction.

Methods:: A retrospective comparison was made between patients who underwent PKP and those that underwent DSEK for corneal endothelial disease. Visual acuity and refractive outcomes were compared post-operatively. For those eyes undergoing DSEK, pre-operative and post-operative endothelial cell counts were compared as well.

Results:: For those eyes undergoing PKP, pre-operative visual acuity ranged from 20/40 to hand-motion, with mean spherical equivalent 0.73±1.5 diopters (D) and mean cylinder 1.04±1.0 D. Post-operative best-corrected visual acuity, measured between 6 and 12 months after surgery, ranged from 20/30 to 20/200. Mean post-operative spherical equivalent was 2.30±4.2 D and mean post-operative cylinder was 5.77±2.7 D. Following PKP, 29% of eyes had best corrected visual acuity of 20/40 or better, and 36% improved greater than two lines of vision. For those eyes undergoing DSEK, pre-operative visual acuity ranged from 20/50 to hand-motion. Mean pre-operative spherical equivalent was 1.68±3.2 D and mean pre-operative cylinder was 1.50±1.4 D. Post-operative visual acuity ranged from 20/25 to finger-count. Post-operative mean spherical equivalent was 2.03±3.0 D and mean cylinder was 1.30±1.5 D. Following DSEK, 60% of eyes had best corrected visual acuity of 20/40 or better, and 80% improved greater than two lines of vision.

Conclusions:: DSEK provides improved visual outcomes and significantly less corneal astigmatism when compared with PKP for the treatment of corneal endothelial dysfunction.

Keywords: cornea: clinical science • cornea: endothelium 
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