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D. A. Taylor, T. John, M. Shimmyo, B. E. Siskowski; Corneal Hysteresis Following Deep Lamellar Endothelial Keratoplasty (DLEK) (Sutureless Corneal Transplant). Invest. Ophthalmol. Vis. Sci. 2007;48(13):4705.
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We sought to measure the corneal biomechanical properties of subjects following DLEK.
96 eyes were studied (Groups 1 & 2). All DLEK patients were operated by a single surgeon (TJ) and the donor corneal disks were surgeon-cut, using manual lamellar dissection and an artificial anterior chamber (AAC) (Bausch & Lomb, Inc.) or an AAC and microkeratome (Moria, Inc.). Intracorneal pocket was dissected in all eyes and a Terry trephine was used to excise the host posterior cornea. There was no anterior or posterior corneal perforation during the dissection. All subjects underwent corneal biomechanical evaluation with the Reichert Ocular Response Analyzer (ORA).
There were 8 eyes of 8 DLEK patients (Gr.1) and 88 eyes of 44 age-matched normal subjects (Gr.2). The demographics- Male/female: 7/1 (Gr.1), 18/26 (Gr.2); Age: (Av±SD) 73±12 yrs (Gr.1), 70±11.5 yrs (Gr.2); Age range: 60-90 yrs (Gr.1), 29-86 yrs (Gr.2); Post-op. days (Av±SD) 1133±447 (Gr.1); Post-op. range 455-1695 days (Gr.1). Corneal hysteresis (CH, Av±SD) 9.01±1.54 (Gr.1), 10.51±1.22 (Gr.2); CH range: 6.20-11.00 (Gr.1), 7.90-14.00 (Gr.2). CH measurements of all DLEK eyes were significantly lower than the normal eyes (P<0.00001).
ORA corneal hysteresis measurements were significantly lower in sutureless corneal graft patients, namely, DLEK than in normal subjects. DLEK has a direct effect on corneal hysteresis and corneal biomechanical properties of the human cornea. This is the first report of CH following DLEK surgery.
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