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R. Nacke, M. Hamill; Preliminary Clinical Results of Posterior Lamellar Keratoplasty in Endothelial Dystrophy and Pseudophakic Bullous Keratopathy Patients. Invest. Ophthalmol. Vis. Sci. 2007;48(13):4714.
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This study presents the 6 month follow-up results of our clinical experience performing posterior lamellar keratoplasty (PLK) in patients with corneal endothelial (Fuch’s) dystrophy and pseudophakic bullous keratopathy.
A retrospective review of all patients with Fuchs Dystrophy or pseudophakic corneal edema undergoing PKL was undertaken. PLK was performed utilizing manually prepared donor buttons and clear corneal or scleral tunnel incisions. Patients with preexisting vision limiting ocular conditions were excluded. Thirty-one patients were followed for 6 months after PLK. Best spectacle-corrected visual acuity (BSCVA), endothelial cell density, and corneal pachymetry were evaluated.
At 3 months after surgery, all transplants were clear and in proper position. BSCVA at 3 months was 20/80 or better in 90% (27/30) of patients while 30% (9/30) had achieved 20/40 or better. At 6 months, BSCVA was 20/80 or better in 100% (26/26) while 42% (11/26) had achieved 20/40 or better. Endothelial cell density averaged 2206 cells/mm2 at 3 months and 2212 cells/mm2 at 6 months. Three month pachymetry averaged 638 µm while 6 month measurements averaged 634 µm.
Posterior lamellar keratoplasty in the setting of endothelial dystrophy and pseudophakic bullous keratopathy is an effective surgical procedure and results in more rapid visual rehabilitation than conventional keratoplasty.
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