May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Diagnosis and Treatment of Scleritis in a Reference Center in Mexico City
Author Affiliations & Notes
  • S. Voorduin
    Uveitis, Instituto de Oftalmologia, Conde de Valenciana, Mexico, Mexico
  • A. Polifroni
    Uveitis, Instituto de Oftalmologia, Conde de Valenciana, Mexico, Mexico
  • M. Pedroza
    Uveitis, Instituto de Oftalmologia, Conde de Valenciana, Mexico, Mexico
  • Footnotes
    Commercial Relationships S. Voorduin, None; A. Polifroni, None; M. Pedroza, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 5838. doi:
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      S. Voorduin, A. Polifroni, M. Pedroza; Diagnosis and Treatment of Scleritis in a Reference Center in Mexico City. Invest. Ophthalmol. Vis. Sci. 2007;48(13):5838.

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Abstract

Purpose:: To evaluate the clinical experience in the diagnosis and management of scleritis in a referral center in Mexico City.

Methods:: Retrospective review of the clinical records of 159 patients (227 eyes) with diagnosis of scleritis in the Instituto de Oftalmologia, Conde de Valenciana in Mexico City between january 2001 and november 2006. Demographic data, laterality of the ocular inflammation, anatomic diagnosis, etiology, treatment (medical or surgical) and complications were evaluated.

Results:: 69.2% of patients were female, medium age was 45.1 years (SD+16.3), medium follow-up time 18 months (range 0-62 months). Average evolution time of the disease was 215 days. 21.4% were bilateral scleritis. 95.6% were anterior scleritis: 44.7% diffuse, 17.6% nodular, 10.1% necrotizing, 3.1% escleromalacia perforans. 68.5% were idiopathic, 16.4% were associated with rheumatoid arthritis, 3.8% herpetic, 2.5% with Wegener's Granulomatosis, 1.3% with tuberculosis, 1.3% with rosacea and 2.9% were postquirurgical. The most common treatment was with non-steroidal antiinflamatory drugs (90.6%), steroids (58%), immunesuppresive chemotherapy (34%) and antibiotics (12%). Five patients required tectonic graft. 40% of patients had complications: scleral thinning (25.2%),catarct (10%), peripheric ulcerative keratitis (8.8%), glaucoma (8.8%), retinal detachment (4.4%), papilitis (1.9%) and ptisis bulbi (1.9%).

Conclusions:: Our population presents important differences with the characteristics described in the literature. Being retrospective, our study has limitations and further prospective investigations must be considered.

Keywords: sclera 
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