May 2007
Volume 48, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2007
Prevalence of Ocular Inflammation in Patients of African Descent With Inflammatory Bowel Disease (Crohn Disease and Ulcerative Colitis) at Howard University Hospital (HUH)
Author Affiliations & Notes
  • K. A. Blakes
    Howard University Hospital, Washington, Dist. of Columbia
    Ophthalmology,
  • R. A. Copeland, Jr.
    Howard University Hospital, Washington, Dist. of Columbia
    Ophthalmology,
  • E. Lee
    Howard University Hospital, Washington, Dist. of Columbia
    Pathology,
  • T. N. Myeni
    Internal Medicine, Boston University, Boston, Massachusetts
  • Footnotes
    Commercial Relationships K.A. Blakes, None; R.A. Copeland, None; E. Lee, None; T.N. Myeni, None.
  • Footnotes
    Support None.
Investigative Ophthalmology & Visual Science May 2007, Vol.48, 5843. doi:
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      K. A. Blakes, R. A. Copeland, Jr., E. Lee, T. N. Myeni; Prevalence of Ocular Inflammation in Patients of African Descent With Inflammatory Bowel Disease (Crohn Disease and Ulcerative Colitis) at Howard University Hospital (HUH). Invest. Ophthalmol. Vis. Sci. 2007;48(13):5843.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose:: To investigate the prevalence of ocular inflammation in patients of African descent with inflammatory bowel disease.

Methods:: A retrospective chart review of patients with a biopsy proven diagnosis of either Crohn disease or Ulcerative Colitis between January 1995 and December 2004 was conducted. Ninety-seven patients were identified with an inflammatory bowel disease. The chart analysis included review of systems, past medical, ocular, social and family histories and an eight part eye exam. We excluded patients less than 18 years of age and those not of African decent.

Results:: Fifty-seven percent (56/97) of the patients had ulcerative colitis, 2% (2/97) had Crohn disease and 41% (39/97) had an indeterminant colitis. Of the 58 patients with a diagnosis of either Ulcerative Colitis or Crohn Disease, only 8 were referred to the Ophthalmology department. Of the eight patients referred, one patient with the diagnosis of ulcerative colitis had multiple episodes of bilateral nongranulomatous uveitis and nodular episcleritis. The prevalence of ocular inflammation in patients of African descent with inflammatory bowel disease was 1% (1/97).

Conclusions:: In our ten year retrospective study of biopsy proven inflammatory bowel disease we found only one patient out ninety-seven to have ocular inflammation. The prevalence of ocular inflammation in patients of African decent with inflammatory bowel disease at HUH is lower than that reported in the literature.

Keywords: inflammation • uveitis-clinical/animal model 
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