Purchase this article with an account.
E. Arrieta, A.C. Acosta, M.A. Orozco, M.G. Aly, I. Riss, B. Weber, S. Davis, L. Pinchuk, F. Fantes, J.–M. Parel; In vivo Correlations Between 70, 100 and 150 µm SIBS Glaucoma Drainage Devices in Rabbits . Invest. Ophthalmol. Vis. Sci. 2006;47(13):28.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To assess the efficacy, safety, biocompatibility ofBPEI–InnFocus glaucoma drainage implant (MiDi) of differentlumen diameters.
22 NZW healthy rabbits were included in this ongoing6 months study: 10 received a 70µm MiDi (A), 6 a 100µm(B), 4 a 150µm (C), and 2 a 300µm (D) control PDMSimplant. 4 surgeons implanted MiDi (11 in OD & 11 in OS)into the anterior chamber via a track made 2mm below the limbuswith the distal end of the device placed under conjunctival–Tenon.Perkins tonometer readings, slit lamp biomicroscopy, gonioscopyand funduscopy was done preop in immediate postop and at POD1, 3, 7, 14, 21, 28, 60 and eye status graded using modifiedMcDonald–Shadduck score system.
All devices were found easy to implant, there was nodifference in implantation time (avg 15.24±5.05 min).Few intraoperative difficulties were observed. No extrusionoccurred, no significant change in average pachymetry was foundand cornea, lens and retina remained normal.
IOP difference between operated and non–operated contralateraleye expressed as a ratio was:
The results at POD 180 will be presented.
All the devices were found easy to implant, safeand biocompatible. The 70 and 100µm MiDi had less collateralcomplications. The larger implants 150 and 300um MiDi were theonly one that had early hypotony. Late IOPs were similar inall the groups.
This PDF is available to Subscribers Only