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A.W. Foong, T.Y. Wong, S.M. Saw, P.J. Foster; Hypermetropia, Axial Length and Hypertension: The Tanjong Pagar Survey . Invest. Ophthalmol. Vis. Sci. 2006;47(13):1156.
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To examine the relationship between hypermetropia, axial length and hypertension.
This population–based, cross–sectional study included 1,213 Chinese persons aged 40–81 years. Hypertension was defined as systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or self–report history of anti–hypertension treatment. Refraction was determined with an auto–refractor and refined subjectively. Moderate hypermetropia was defined as ≥+2.00 spherical equivalent diopters (D), mild hypermetropia as +0.75 to +1.75 D, emmetropia as –0.50 to +0.50 D, low myopia as –0.75 to –2.75 D, moderate myopia as –3.00 to –5.75 D, and high myopia as ≤–6.00 D. A–mode ultrasound was used to measure axial length.
The crude odds ratio of hypertension was 2.5 (95% confidence intervals [CI], 1.4–4.6) for moderate hypermetropia versus high myopia (p trend=0.038), and 1.4 (95% CI 0.9–2.1) for highest versus lowest axial length quintile (p trend=0.043). These associations were no longer significant after adjustment for age, and additionally for gender, education, housing type and income.
These data provide no evidence that hypermetropia or shorter axial length is independently associated with hypertension.
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