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S. Kimura, S. Hasebe, M. Miyata, I. Hamasaki, J. Suemaru, H. Ohtsuki; Repeatability of Axial–Length Measurement Using Zeiss IOLMaster in a Myopia Control Trial . Invest. Ophthalmol. Vis. Sci. 2006;47(13):1167.
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© ARVO (1962-2015); The Authors (2016-present)
Higher precision of axial length (AL) measurement using Zeiss IOLMaster (a non–contact optical device using partial coherence interferometry) compared to that with conventional A–scan ultrasonography was recently reported. This study investigated the repeatability of those findings in myopic children of different ages and refractive power.
In 95 children participating in a myopia control trial with progressive addition lenses in Japanese schoolchildren (mean age: 10.9+/–1.4 years, age range: 6–14 years, –6.00 < SE < –1.00 D, astigmatism <1.50 D), AL was measured using IOLMaster. An average of three successive readings was regarded as a representative value. Five minutes after the initial measurement, measurement for the right eye was performed again. The 95% limits of agreement of the two values obtained on different occasions (repeatability) were calculated. The AL was also compared with refractive errors measured by cycloplegic autorefraction (RE) and corneal refractive power (CRP).
The repeatability of the AL measurement was +/– 0.044mm, which corresponds to +/–0.13 D, and did not significantly differ with age or degree of myopia. The AL was moderately correlated with RE (AL = –0.27xRE+24.15, R=–0.42) and CRP (AL = –0.44xCRP+44.68, R=–0.44). There were no apparent side effect.
Probably due to rather large fixation and/or head instability found in children, the repeatability of AL measurement with IOLMaster was slightly poorer than that reported for adults. However, repeatability was twofold better when compared with the reported repeatability for cycloplegic autorefraction or of AL measurement by A–scan ultrasonography. Considering the high precision as well as ease of clinical application, IOLMaster is a useful tool for evaluating myopia progression as well as therapeutic effects in myopia control trials.
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