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Y. Okamoto, C. Okamoto, T. Samejima, T. Tokunaga, K. Miyata, T. Oshika; Contrast Sensitivity Function and Ocular Higher–Order Wavefront Aberrations in Normal Human Eyes . Invest. Ophthalmol. Vis. Sci. 2006;47(13):1198.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the relation between contrast sensitivity function and ocular higher–order wavefront aberrations in normal human eyes.
In 307 eyes of 161 normal subjects, ranging in age between 15 to 60 years (30.9 ± 8.0 years, mean ± standard deviation), ocular higher–order aberrations were measured for a 4–mm pupil using the Hartmann–Shack wavefront analyzer (Topcon KR–9000PW). The root–mean–square of the third– and fourth–order Zernike coefficients was used to represent coma–like and spherical–like aberrations, respectively. We measured contrast sensitivity using CSV–1000E (Vector Vision), low contrast visual acuity using CSV–1000LanC10%, and letter contrast sensitivity using CSV–1000LV. From the data of CSV–1000E, the area under the log contrast sensitivity function (AULCSF) was calculated.
Multiple linear regression analysis revealed that coma–like aberration had a significant correlation (p=0.002) with AULSCF, but spherical–like aberration (p=0.208) and age (p=0.185) did not. For low contrast visual acuity, coma–like aberration showed significant contribution (p<0.001), but spherical–like aberration (p=0.250) and age (p=0.258) did not. For letter contrast sensitivity, coma–like aberration was found to be significantly relevant (p<0.001), but spherical–like aberration (p=0.155) and age (p=0.855) were not.
In normal human eyes, coma–like aberration of the eye significantly influences contrast sensitivity function.
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