May 2006
Volume 47, Issue 13
ARVO Annual Meeting Abstract  |   May 2006
Link Between Trypan Blue And Posterior Capsule Opacification
Author Affiliations & Notes
  • S. Milazzo
    Department, Saint, Amiens, France
    Ophthalmology, Clinic Saint Victor, Amiens, France
  • F. Denimal
    Department, Saint, Amiens, France
  • B. Jany
    Department, Saint, Amiens, France
  • Footnotes
    Commercial Relationships  S. Milazzo, None; F. Denimal, None; B. Jany, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 667. doi:
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    • Get Citation

      S. Milazzo, F. Denimal, B. Jany; Link Between Trypan Blue And Posterior Capsule Opacification . Invest. Ophthalmol. Vis. Sci. 2006;47(13):667.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : To describe clinical findings, long term complications, incidence of posterior capsule opacification (PCO) after cataract surgery using trypan blue, because this dye is cytotoxic in vitro.

Methods: : A retrospective study included 20 eyes of 20 patients having mature cataract. The surgical procedure used trypan blue for anterior capsulorhexis. Phacoemulsification and implantation were without peroperative complication. The mean follow–up was of 3.2 years(2 to 5 years). Visual acuity, endothelial cell count, anterior chamber reaction, intraocular pressure, IOL deposits,PCO were documented at 1 week, 1 and 6 months, and every year.

Results: : There was no incidence about endothelial cell count, or intraocular presuure. No IOL deposits were observed. 5 eyes presented PCO.

Conclusions: : Trypan blue 1% seems to be safe, so no incidence, particularly a decrease of PCO because an eventual cytotoxicity, was observed at long term.

Keywords: drug toxicity/drug effects • cataract • clinical (human) or epidemiologic studies: outcomes/complications 

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