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H. Nomoto, M. Kageyama, A. Yamashita, K. Fukuda, H. Yamaji, F. Shiraga; Relationship Between Retinal Sensitivity With Micro Perimeter and Retinal Thickness With Optical Coherence Tomography in Eyes With Diabetic Macular Edema . Invest. Ophthalmol. Vis. Sci. 2006;47(13):992.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the correlation between retinal sensitivity measured with micro perimeter (MP–1) and retinal thickness with optical coherence tomography (OCT) in eyes with diabetic macular edema (DME).
A prospective study was done in 33 eyes of 26 patients with DME. The age of the patients of ranged from 51 to 76 (mean 58.8 ± 11.8 years). Foveal retinal thickness ranged from 239 to 927 µm (mean 517 ± 142 µm). We classified the type of DME into 3 types: retinal swelling type (16 eyes), cystoid macular edema type (9 eyes) and serous retinal detachment type (8 eyes). OCT was performed with the Fast Macular Thickness Map protocol (six 6 mm radial line scans). The data were analyzed with Retinal Map program, which divided the macular area with 6 mm diameter into 9 fields, and we obtained the mean retinal thickness in each field. Retinal sensitivities were measured with MP–1(stimulus duration: 200msec, threshold strategy: 4–2–1). We used a new stimulus pattern with 37 stimulating points (Goldmann III size) corresponding to each field of Retinal Map program.
The mean retinal sensitivity was significantly correlated with the mean retinal thickness in retinal swelling type (r = 0.49, P < 0.0001; y = 544.5–12.1x) and cystoid macular edema type (r = 0.70, P < 0.0001; y = 698.6–26.1x), however, no correlation in serous retinal detachment type (r = 0.11, P = 0.37; y = 599.6–4.0x).
In eyes with DME, retinal sensitivity is correlated with retinal thickness in retinal swelling type and cystoid macular edema type in 9 fields of Retinal Map program of OCT. Especially in eyes with cystoid macular edema type, there is a strong correlation between retinal sensitivity and retinal thickness.
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