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K.M. Rocha, W. Nose, M. Chalita, A.N. Yamada, L. Morimoto, K. Bottós, J. Bottós, E. Soriano; Wavefront Analysis and Contrast Sensitivity of Aspheric and Spherical IOLs: A Randomized Prospective Study . Invest. Ophthalmol. Vis. Sci. 2006;47(13):1502.
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© ARVO (1962-2015); The Authors (2016-present)
To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration and other terms of HOA) and contrast sensitivity under different light conditions in 120 eyes implanted with one monofocal aspheric blue light filter IOL and two spherical IOLs.
A randomized prospective study comparing three IOLs types Alcon AcrySof IQ (40 eyes), Acrysof Natural (40 eyes) and AMO Sensar (40 eyes) was carried out. The cataract surgeries were performed by two experienced surgeons. Complete ophthalmological exam including UCVA, BSCVA, corneal topography, contrast sensitivity (Pelli–Robson chart,Optec® 6500) and wavefront analysis were performed preoperatively, 30 and 90 days postoperatively. The Optec contrast sensitivity test was performed under photopic and mesopic conditions, with and without glare. Patients with PAM worse than 20/32, any ocular pathology or surgical complications were excluded. Statistical analysis was performed and p≤0.05 was considered statistically significant.
All eyes in all groups had postop BSCVA≥ 20/25. Mean total aberration RMS values were: 0.75±0.35µm (AcrysofIQ); 1,35±0.40µm (SN60) and 1.25±0.43µm (Sensar). Mean HOA values were: 0.26±0.05µm (AcrysofIQ); 0.38±0.06 (SN60) and 0.31±0.06 (Sensar). Mean spherical aberration values were: 0.02±0.04µm (AcrysofIQ); 0.25±0.04 (SN60) and 0.17±0.07 (Sensar). The AcrysofIQ IOL showed statistically significant less induction of spherical aberration and lower values of total and HOA when compared to the other IOLs (p<0.05). No statistically significant difference was found between SN60AT and Sensar. Mean Pelli–Robson contrast sensitivity values were:1.62±0.08 (AcrysofIQ); 1.59±0.10 (SN60) and 1.58±0.10 (Sensar). There were no statistically significant contrast sensitivity differences between the three groups in photopic and mesopic with glare conditions using Functional Acuity Contrast Test (Optec 6500). Under mesopic condition there were statistical difference between the AcrysofIQ group and the others, specific in 3 and 6 cpd spatial frequencies.
The aspheric IOL (Acrysof Natural IQ) induced significantly less spherical aberration and HOA when compared to the spherical IOLs analyzed in this study. Pelli–Robson contrast sensitivity under photopic conditions revealed greater values with AcrysofIQ but it was not statistically significant. The aspheric IOL group showed better night contrast sensitivity results.
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