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G.J. Coscas, F. Coscas, G. Mimoun, M. Papp–Pawlack, E. Souied, G. Soubrane; Comparative Evaluation Using Auto Fluorescence and Slo Icg Images During Follow–Up of Pdt Management of Occult Cnv in Amd . Invest. Ophthalmol. Vis. Sci. 2006;47(13):2140.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate and compare the fundus auto fluorescence images (FAF) and late phase SLO ICG–A of eyes with occult CNV during follow up
Observational case series. Fifty–four patients seen in tertiary referral centre. Confocal digital infrared reflection images (excitation, 830 nm) and fundus auto–fluorescence images (excitation, 488 nm) were recorded with a confocal scanning laser ophthalmoscope (Heidelberg Retina Angiograph; Heidelberg Engineering, Heidelberg, Germany). Red–free ,infrared monochromatic images and auto–fluorescence and fluorescein and ICG– SLO angiography were obtained before and after treatment
Late stage SLO–ICG images showed in most of the cases a late hyper fluorescence plaque with sharply delimited but irregular borders. During follow up, extension in the area and scalloped borders were associated with accentuation of lesion. Recurrences of neovascularization were detectable as early and persistent hyper fluorescent areas. FAF images showed dark areas correlated with the ICG plaques but in all eyes smaller and of irregular density. An hyper fluorescent halo was present in all active and progressive cases
SLO–ICG examination was effective for detection of persistant or recurrent active CNV. Auto–fluorescence images may indicate the extend of compromised RPE and may, therefore, be valuable for analysis and for prognostic value.
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