May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Prevalence of Age–Related Maculopathy in an Elderly Chinese Population in Taiwan: The Shihpai Eye Study
Author Affiliations & Notes
  • C.–Y. Cheng
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
    Inherited Disease Research Branch, National Human Genome Research Institute, Baltimore, MD
  • S.–J. Chen
    Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan Republic of China
    Community Medicine Research Center and Institute of Public Health, National Yang Ming University, Taipei, Taiwan Republic of China
  • H.–Y. Tsai
    Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan Republic of China
  • W.–M. Hsu
    Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan Republic of China
    Department of Ophthalmology, National Yang Ming University School of Medicine, Taipei, Taiwan Republic of China
  • J.–H. Liu
    Department of Ophthalmology, National Yang Ming University School of Medicine, Taipei, Taiwan Republic of China
    Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan Republic of China
  • P. Chou
    Community Medicine Research Center and Institute of Public Health, National Yang Ming University, Taipei, Taiwan Republic of China
  • Footnotes
    Commercial Relationships  C. Cheng, None; S. Chen, None; H. Tsai, None; W. Hsu, None; J. Liu, None; P. Chou, None.
  • Footnotes
    Support  VGH Grant 89–404, Yen Tjing Ling Medical Foundation
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 2212. doi:
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      C.–Y. Cheng, S.–J. Chen, H.–Y. Tsai, W.–M. Hsu, J.–H. Liu, P. Chou; Prevalence of Age–Related Maculopathy in an Elderly Chinese Population in Taiwan: The Shihpai Eye Study . Invest. Ophthalmol. Vis. Sci. 2006;47(13):2212.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Few epidemiologic data are available on age–related maculopathy (ARM) in elderly Asians. The study was to determine prevalence and risk factors associated with ARM in an elderly Chinese population in Taiwan.

Methods: : A population–based survey was conducted in the Shihpai district of Taipei, Taiwan. A total of 2,045 residents 65 years of age or older were randomly selected and invited to complete a comprehensive questionnaire and undertake a detailed ocular examination, including indirect ophthalmoscopy and fundus photography. Of the subjects, 1361 (66.6%) participated in the ocular examination. ARM was defined according to the international classification and grading system.

Results: : ARM was present in 145 subjects–an age–sex–adjusted prevalence of 10.65% (95% confidence interval [CI], 9.04%–12.27%). The prevalence increased from 7.69% in the 60– to 69–year group to 16.24% in the group aged 80 years and older. Men had a significantly higher rate of ARM than women (12.53% vs. 7.79%, respectively; P = 0.006). Multivariate regression analysis showed that the prevalence of ARM was significantly higher in those 75 years of age or older (odds ratio [OR], 2.43; 95% CI, 1.71–3.47) and in men (OR, 1.78; 95% CI, 1.21–2.60). Current cigarette smoking was associated with a modestly increased prevalence of ARM (OR, 1.52; 95% CI, 0.98–2.35). There was no significant association between ARM and alcohol drinking, history of hypertension, or body mass index.

Conclusions: : The prevalence of ARM in this Chinese population is much lower than those reported in similarly aged white populations.

Keywords: age-related macular degeneration • clinical (human) or epidemiologic studies: prevalence/incidence • clinical (human) or epidemiologic studies: risk factor assessment 
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