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A.L. Skarin, R. Elborgh, E. Edlund, E. Bengtsson–Stigmar; Long–Term Follow–Up of 55 Patients With Uveitis Associated With Juvenile Idiopathic Arthritis . Invest. Ophthalmol. Vis. Sci. 2006;47(13):2433.
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To examine the clinical and visual outcome of patients with Juvenile Idiopahtic Arthritis (JIA)–associated uveitis 7 and 24 years after onset of the eye disease.
Fifty–five patients who developed JIA–associated uveitis and who were treated for JIA between 1973 and 1982 at the Department of Pediatric Rheumatology were retrospectively evaluated after 7 years of eye disease. Forty–nine of these were also evaluated after 24 years of eye disease.
Fifty–five (15.7%) out of 350 patients with JIA developed uveitis. Forty–six (84%) of the patients had oligoarthritis, 6 (11%) had polyarthrits and 3 (5%) had systemic disease. At 7 years some form of ocular complication was seen in 32 (58%) of the patients. Cataract was seen in 19 (34%)of the patients at 7 years and in 28 (51%) of the patients at 24 years. Uveitic glaucoma was seen in 3 (5%) at 7 years and in 12 (22%) at 24 years follow–up. Half of the patients (27/55) still had active uveitis at 24 years. Visual reduction occurred mainly during the first 7 years. Thereafter visual acuity was not significantly reduced. A statistically significant increase in the incidence of cataract and uveitic glaucoma was seen between the 7th and 24th year of disease.
Twenty–four years after onset of JIA–associated uveitis the inflammatory eye disease was still active in approximately 50 % if these Swedish patients. The results indicate an increased risk for further visual reduction later in life.
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