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J.J. Augsburger, Z.M. Correa, N. Trichopoulos; Practical Clinical Classification of Intraocular Lymphoid Tumors and Infiltrations . Invest. Ophthalmol. Vis. Sci. 2006;47(13):2819.
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To propose a practical classification of intraocular lymphoid tumors and infiltrations.
Retrospective descriptive report based on over 25 years of subspecialty practice of ocular oncology.
The clinical classification of intraocular lymphoid tumors and infiltrations we use in our ocular oncology practice divides patients into the following categories: 1. Primary intraocular lymphomas
a. Primary vitreoretinal lymphoma
b. Primary uveal lymphoma
c. Primary intraocular lymphoma with both vitreoretinal and uveal features
d. Miscellaneous other primary intraocular lymphomas
2. Metastatic intraocular lymphomas
3. Intraocular involvement by lymphoid leukemias
4. Intraocular lymphoid hyperplasias
5. Intraocular lymphoid inflammations
The authors will discuss and illustrate the characteristic clinical and pathologic features of each category, recommend an approach to diagnosis and staging for patients with each category, and summarize currently available information about management for each category.
The spectrum of intraocular lymphoid tumors and infiltrations is quite broad. Correct classification of the patient is likely to lead to an appropriate baseline staging evaluation and improved ability to assess the effectiveness of alternative interventions for that category of disease.
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