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G.F. Schmid; Central And Peripheral Retinal Thickness In Healthy, Emmetropic Children . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3298.
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© ARVO (1962-2015); The Authors (2016-present)
Abnormal retinal thickness often allows the early diagnosis of ocular disorders, and knowledge of a normal retinal thickness range is therefore of utmost importance. Such knowledge from precise measurements is currently availabale only for the central (macular) areas in adult eyes. We used Optical Low Coherence Reflectometry (OLCR) to precisely measure retinal thickness, the distance from the vitreo–retinal interface to the retinal–choroidal interface, in children at four locations 20° in the peripheral retina and at the fovea.
Retinal thickness at 20° in the nasal, temporal, inferior and superior retina and at the fovea was measured in right eyes of 46 healthy, functionally emmetropic children 7–11 years of age during cycloplegia by obtaining consecutive OLCR scans at each of the assessed locations. Average retinal thickness and standard deviations were calculated at each of the retinal locations, and differences in retinal thickness between the retinal locations were analyzed with a one–factor ANOVA. The measurement precision was evaluated. Optical delay was converted to geometrical thicknesss using a retinal refractive index of 1.38.
Average retinal thickness at the five assessed locations ranged from 230 µm at the inferior retina to 267 µm at the temporal retina, where retinal thickness was significantly larger than at the other peripheral locations (p=0.002). Foveal retinal thickness was 249 µm, greater than the 150–160 µm that were measured in adult eyes with OCT and reported in earlier studies. The average measurement precision was 15 microns as estimated by the standard deviation of consecutive measurements. It was the same at the different retinal locations.
Retinal thickness in healthy, emmetropic children measures 248 on average and is approximately constant up to 20° into the peripheral retina, except for the temporal location, where it is slightly larger. Significant deviations from this normal thickness may indicate the presence, and permit the early detection, of an ocular disorder.
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