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P.A. Netland, K. Ishida, B. Khan, I.I. Ahmed; Ahmed Glaucoma Valve Implantation in Eyes With or Without Silicone Oil . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3548.
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To compare the results of Ahmed Glaucoma Valve implantation in eyes with silicone oil to those without silicone oil.
In this retrospective comparative case–control study, we reviewed 68 eyes of 68 patients, comparing the surgical outcomes in eyes with silicone oil (N=34) to matched patients without silicone oil (N=34). Success was defined as intraocular pressure (IOP) of 6 mmHg and 21 mmHg, with or without the use of glaucoma medicines, without further glaucoma surgery, and without loss of light perception.
Average follow–up was 21 mo for silicone oil group and 24 mo for control (P=0.11). Mean IOP within 2 weeks postoperatively was significantly higher in the silicone oil group (P<0.05) and hypertensive phase within 6 mo was observed more frequently in the silicone group than in the control group (P<0.01). However, mean IOP at last follow–up was comparable between the 2 groups (15.1 7.3 mmHg in silicone oil group and 15.0 3.8 mmHg in control, P=0.60). The mean number of glaucoma medications was 1.2 1.2 and 1.6 1.3 (P=0.14) in silicone oil group and control, respectively, at the most recent follow–up. Cumulative probability of success by life–table analysis was 73% at 1 year, 66% at 2 yrs, and 44% at 4 yrs in silicone oil group, and 100% at 1 year, 89% at 2 yrs, and 67% at 4 yrs, respectively.(P=0.01). Complications were comparable between 2 groups (P>0.05). In 14 (43%) of 34 silicone treated eyes, silicone was observed adhering to the tube in the anterior chamber after surgery.
Eyes treated with silicone oil have a poor prognosis for surgical success after Ahmed Glaucoma Valve implantation compared with eyes not treated with silicone oil.
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