May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
The Agreement Between HRT and OCT on Optic Disk Area Measurements in Patientes With Peripapilar Atrophy
Author Affiliations & Notes
  • M.T. Leite
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • K.M. Bottós
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • C.M. F. Carossa
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • L.M. Cruz
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • P.A. A. Mello
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • A. Paranhos, Jr.
    Ophthalmology, Federal University of Sao Paulo, Sao Paulo, Brazil
  • Footnotes
    Commercial Relationships  M.T. Leite, None; K.M. Bottós, None; C.M.F. Carossa, None; L.M. Cruz, None; P.A.A. Mello, None; A. Paranhos, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 3628. doi:
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    • Get Citation

      M.T. Leite, K.M. Bottós, C.M. F. Carossa, L.M. Cruz, P.A. A. Mello, A. Paranhos, Jr.; The Agreement Between HRT and OCT on Optic Disk Area Measurements in Patientes With Peripapilar Atrophy . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3628.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the influence of the optical nerve head atrophy on the agreement between HRT and OCT on optic disk area measurements.

Methods: : 87 glaucomatous eyes were selected by HRT II measurements with different levels of peripapilar atrophy. 87 images of OCT Stratus and HRT measurements of optic disk area, rim area, cup area and cup to disk area ratio were taken. Atrophy area was considered as the measure of the difference between the atrophy (including optic nerve area) minus optic nerve area. Delta optic disk area (Delta ODA) was defined as HRT – OCT disk area (agreement between the two devices). The statistical analyses: Delta ODA as dependent variable and peripapilar atrophy area as independent variable was analyzed in a linear regression model. The difference between the mean of ODA measured by the two devices was evaluated by Student t–test.

Results: : There was a significant but not clinically relevant difference between the mean of ODA measured by HRT (2,22 ± 0,62 mm2) and OCT (2,49 ± 0,51mm2); p<0,0001. No statistic difference was found in rim area analysis measured by HRT (1,39 ± 0,41mm2) and OCT (1,29 ± 0,47mm2); p=0,097. The cup area analysis showed a significant higher values on OCT (1,23 ± 0,72mm2) than HRT (0,82 ± 0,54mm2); p<0,00001. Cup to disk area analysis showed a significant difference between the mean of HRT (0,36 ± 0,23) and OCT (0,47±0,22); p<0,00001. There were no significant association regarding Delta ODA and the area of optic disk atrophy (Pearson Correlation Coefficient = 0,06; p=0,625).

Conclusions: : Although optic nerve area measured by OCT depends on the automatic definition of where the retinal pigment epithelium ends, and this is not the case on HRT, Delta ODA was not influenced by agreement between the two devices for this variable.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • optic disc • imaging/image analysis: clinical 
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