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H. Nomoto, C. Matsumoto, S. Takada, S. Okuyama, S. Hashimoto, E. Arimura, Y. Shimomura; Correlations Between Nerve Fiber Layer Thickness Measurements by OCT and Visual Field Findings With SAP, FDT SWAP and Flicker Perimetry . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3666.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the correlation of structural findings derived from OCT with SAP, FDT, SWAP and Flicker field data in patients with open–angle glaucoma (OAG) and glaucoma suspects.
Fifty eyes of 50 patients with OAG and glaucoma suspects were tested by HFA 24–2 full threshold (SAP), SITA SWAP, FDT Matrix (24–2–5, 24–2–1), and flicker perimetry (4–zone 38S) using Octopus 311. The visual fields was divided into 6 sectors and the number of abnormal points in each sector was evaluated. The correlation between functional and structural changes in the visual field was investigated with respect to the average nerve fiber layer thickness (NFLT),superior average thickness, inferior average thickness and NFLT in 12 clock hour sectors using Stratus OCT.
Significant correlations of the average NFLT with mean deviation (MD) of SAP, with the numbers of abnormal points in the SAP, FDT, SWAP and Flicker field data were observed. In the early stage of OAG (MD > –6dB) and glaucoma suspects, the average NFLT correlated with the number of the abnormal points in the FDT, SWAP and flicker field except in SAP. Particularly in the early stage of OAG and glaucoma suspects, some specific NFLT sectors were more significantly correlated to the anatomically corresponding visual field sectors assessed by FDT, SWAP and flicker perimetry than by SAP.
In the early stage of OAG, the functional changes assessed by FDT, SWAP and flicker perimetry significantly correlate with the structural changes by OCT.
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