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I. Maruko, S. Ise, T. Sekiryu, H. Koizumi, M. Saito, T. Iida; The Number of Microaneurysm After Intravitreal Triamcinolone Acetonide Injection . Invest. Ophthalmol. Vis. Sci. 2006;47(13):3845.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the changes in the number of microaneurysms (MA) after intravitreal triamcinolone acetonide (TA) injection for diabetic macular edema.
Thirteen eyes of 13 patients (6 men and 7 women, average 62.6 year) with diabetic macular edema were received the intravitreal TA injection. All patients underwent a fluorescein angiography (FA) and optical coherence tomography (OCT) before and after treatment. We counted the number of MA within 2 disc diameters in size at the macular area on FA. We also evaluated the number of MA in the second eye (not treated eye) of each patient.
The average of the number of MA in treated eyes significantly decreased from 48.8±26.9 (mean ± SD) before treatment to 45.5±26.3 after treatment (p=0.006). In the second eyes, the number of MA significantly increased from 45.6±18.9 to 51.2±20.8 (p=0.003). There was a significant difference in the change of MA count between treated eyes and not treated eyes. Diabetic macular edema improved on OCT in all eyes after intravitreal TA injection.
Our current study revealed that the number of MA decreased after intravitreal TA injection. The reduction of the number of MA after intravitreal TA could participate the improvement of diabetic macular edema.
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