May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
The Clinical Role of SLO–OCT in Diagnosing and Managing Recurrent Cystoid Macula Edema in a Patient With Retinitis Pigmentosa Responsive to Acetazolamide Treatment
Author Affiliations & Notes
  • A.C. Brown
    New York Eye and Ear Infirmary, New York, NY
  • S. Lalin
    New York Eye and Ear Infirmary, New York, NY
  • R. Rosen
    New York Eye and Ear Infirmary, New York, NY
  • Footnotes
    Commercial Relationships  A.C. Brown, None; S. Lalin, None; R. Rosen, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 4040. doi:
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      A.C. Brown, S. Lalin, R. Rosen; The Clinical Role of SLO–OCT in Diagnosing and Managing Recurrent Cystoid Macula Edema in a Patient With Retinitis Pigmentosa Responsive to Acetazolamide Treatment . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4040.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Demonstrate the clinical utility of SLO–OCT imaging in diagnosing and managing cystoid macula edema in Retinitis Pigmentosa

Methods: : A case report of a 48 year–old man with advanced Retinitis Pigmentosa who developed recurrent cystoid macular edema responsive to acetazolamide treatment. Outcome measures are visual acuity and central retinal thickness based on SLO–OCT imaging.

Results: : The patient presented with progressively worsening vision from 20/20 to 20/50 in the right/left eye and was treated with 500 mg sequels of acetazolamide with resolution of the cystoid macula edema and demonstrated on SLO–OCT imaging. In addition, the patient’s visual acuity improved to 20/25. The patient’s acetazolamide was then gradually tapered off over the next six months with the vision remaining stable in that time frame. The patient returned for follow–up, 2 months after the acetazolamide was discontinued with recurrent cystoid macula edema confirmed by SLO–OCT and decreased visual acuity to 20/40. The patient was re–started on 500mg sequels of acetazolamide and returned 2 weeks later with complete resolution of the cystoid macula edema on SLO–OCT imaging and visual acuity improved to 20/25.

Conclusions: : SLO–OCT provides a clinically objective way of diagnosing and managing cystoid macula edema in patient with Retinitis Pigmentosa as in this sub–group of patients the fluorescein angiography often does not demonstrate hyperfluorescence or leakage.

Keywords: imaging/image analysis: clinical • macula/fovea • retinitis 
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