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M. Kojima, Y. Yamashiro, H. Sasaki, J.–T. Qu, M. Hanazawa, K. Wake, S. Watanabe, M. Taki, Y. Kamimura, K. Sasaki; Investigation of Safety Exposure Range by 60 Ghz Millimeter–Wave for Rabbit Eyes . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4077.
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© ARVO (1962-2015); The Authors (2016-present)
Millimeter–wave bands have started to be used in various wireless applications such as data transmission and collision avoidance devices for cars in our life. This study was designed to investigate safety exposure range, ocular changes, progression and healing in rabbits by 60 GHz millimeter–wave exposure.
The eyes of pigmented rabbits were exposed unilaterally to a 60 GHz millimeter–wave with lens antenna. Rabbits received systemic and topical anesthesia during exposure and ocular examinations. 10, 1,500, and 3,000 mW/cm2 for 6 minute exposures was given to investigate the effects of ocular changes. Ocular changes were evaluated by slit lamp, laser flare meter, and iris angiography.
Miosis and iris vasodilation but no corneal opacity was observed immediately after exposure with 3,000 mW/cm2. Corneal opacification and corneal epithelial damage were seen 1 to 7 days after exposure. Corneal opacification remained for over 7 weeks after exposure. Lens epithelial cell flat preparation showed cell damage in the pupil area 1 to 3 days after exposure. But lens was kept transparent. Through 1,500 mW/cm2 exposures, a half of rabbit in this group showed the same symptoms of 3,000 mW/cm2 exposure group. All ocular changes were healed within a week in the 1,500 mW/cm2 exposure group. No ocular changes were observed in the group of 10 mW/cm2 exposure.
10 mW/cm2 do not show any ocular changes in rabbit eyes. *This study was supported safety guideline study of Ministry of Internal Affairs and Communications of Japan.
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