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N. Duchateau, L. Haddad, D. Monnet, E. Delaire, C. Elie, R.D. Levinson, A.P. Brézin; Comparison Between Two Protocols of Macular Imaging by Optical Coherence Tomography in Patients with Birdshot Chorioretinopathy . Invest. Ophthalmol. Vis. Sci. 2006;47(13):4504.
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© ARVO (1962-2015); The Authors (2016-present)
To compare results obtained with the Fast Imaging protocol with results from Standard Macular Imaging by Optical Coherence Tomography (OCT) in patients with Birdshot chorioretinopathy.
Eighty patients with Birdshot chorioretinopathy, seen in a single center, were included. Optical Coherence Tomography was performed with an OCT3 (OCT3 Zeiss–Humphrey, San Leandro, CA, USA). Two protocols of acquisition were used: Macular Thickness Map (MTM) and Fast Macular Thickness Map (FMTM). MTM was based on consecutive acquisitions of 6 sections with 512 A–scans and FMTM was based on simultaneous acquisitions of 6 sections with 128 A–scans. Intraclass correlation coefficients were calculated for macular thickness in 1 mm diameter (A1), foveal thickness and macular volume. The duration of both examination methods was timed during a repeat visit visit for a subgroup of 40 patients.
The mean duration of acquisition was 65.6 seconds with the MTM protocol and 9.6 seconds with the FMTM protocol. Measurements by MTM and FMTM were respectively 187 ± 98.5 µm (range 85–768) and 197 ± 114.7 µm (range 84–826) for average foveal thickness, 224 ± 87.3 µm (range 118–768) and 228.5 ± 104 µm (range 118–804) for average macular thickness (A1), and 7.1 ± 1.4 mm3 (range 4.6– 14.7) and 7,0 ± 1.6 mm3 (range 4.2–15.3) for average macular volume. The intraclass correlation coefficient was 0.98 [95% CI 0.95–0.99] for macular thickness, 0.97 [95% 0.94–0.99] for foveolar thickness and 0.92 [95% CI 0.95–0.99] for macular volume. The mean of the differences between standard and fast protocol was –3.8 µm for foveal thickness (paired t–test, p=0.008) and –10.6µm for macular thickness (p<0.001). No statistical difference was observed for macular volume.
Results from Fast and Standard macular imaging by OCT were highly correlated, but with slightly greater measurements of macular thickness using Fast macular imaging.
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