Purchase this article with an account.
A. Capone, Jr., The PHOTOROP Study Group; Evolution of Retinal Detachment in Posterior ROP in the PHOTOROP Study . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5305.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To report on the clinical and demographic features of a group of infants enrolled in the PHOTOROP Study which went on to develop bilateral retinal detachment despite timely and apporpriate peripheral retinal ablation.
Prospective observational case series.
Ten eyes of five infants comprise the study cohort. Mean postmenstrual age was 24 6/7 weeks and mean birthweight 650 grams. There were 3 female infants and 2 males. One infant was African–American, two were hispanic, and two were caucasian. Mean age at the time of retinal ablation was 35 weeks. All eyes were fully treated. Mean age at retinal detachment was 39 weeks. All infants had bilateral agressive posterior (zone 1) retinopathy of prematurity. The clinical appearance of these eyes was characterized by fine flat neovascularization located predominantly nasally, without a clearly apparent shunt vessel. The clinical course was characterized by an initial reductrion of plus disease, with subsequent reappearance of plus disease and progression to detachment.
Eyes with posterior ROP may initially appear to regress, with subsequent reactivation and progression to retinal detachment, despite appropriate ablative treatment of the peripheral retina.
This PDF is available to Subscribers Only