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F. Molle, D. Lepore, M.M. Pagliara, A. Baldascino, R. De Santis, G. D'Amico, C. Angora, L. Orazi, M. Laguardia, E. Balestrazzi; Early Vitrectomy for ROP . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5312.
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according to ET ROP study 19,9% of ROP progrees to stage 4 and 5 despite avacsular retina photoablation. The purpose of this study is to evaluate if early vitrectomy could represent a useful treatment for ROP in case of laser failure.
from jan 1st 2004 to june 30 2005 14 inborn preterm (28eyes), with mean gestational age (GA) 26,14 weeks (range 24–30wks) and a mean birth weight (BW) 739,29gr (460–1250gr) were treated with laser. Three babies (6eyes) progressed to stage 5 and 2 eyes (1 baby) to stage 4b despite laser. Two port lens–sparing vitrectomy (LSV) was performed in these cases at a mean postconceptional age of 38,16 weeks (range 33,1–42,0wks).
structural outcomes at six–month follow–up are presented here. In one baby (2 eyes) partial retinal reattachment was achieved. Two eyes from 1 baby showed a massive retinal degeneration despite partial reattachment. Resumption of preretinal fibrous proliferation requiring reintervention, was observed in 4 eyes.
From literature LSV is the only therapy porposed for ROP after laser failure. In our experience only 2 on 8 eyes showed retinal stabilisation and RLF prevention. Although some light perception was clearly still present in these eyes LSV usefulness remains questionable.
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