May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Normal Age–Related Values for Fundus–Related Perimetry (Microperimetry) with MP1 Microperimeter
Author Affiliations & Notes
  • E. Midena
    Department of Ophthalmology, University of Padova, Padova, Italy
  • F. Cavarzeran
    Department of Ophthalmology, University of Padova, Padova, Italy
  • Microperimetry Study Group
    Department of Ophthalmology, University of Padova, Padova, Italy
  • Footnotes
    Commercial Relationships  E. Midena, None; F. Cavarzeran, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 5349. doi:
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      E. Midena, F. Cavarzeran, Microperimetry Study Group; Normal Age–Related Values for Fundus–Related Perimetry (Microperimetry) with MP1 Microperimeter . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5349.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the normal, age–related light sensitivity values for fundus–related perimetry in normal volunteers of different ages.

Methods: : Automatic, full–threshold fundus–related perimetry (microperimetry) of the central field (20 x 20 degrees, 77 stimulated points) by means of the MP1 Microperimeter (Nidek Technologies, Italy) was performed on 349 eyes of 176 healthy persons aged 20 to 75 years with normal vision and no eye disease. Fixation was simultaneously documented. Light sensitivity values were evaluated according to each subject’s age and test point location. Linear regression analysis and distribution–free estimation of age–related centiles were used for the statistical analysis

Results: : Linear regression analysis revealed a significant (P<.0001) decrease of the mean sensitivity starting with 19.7 db at age of 20 years. These results were confirmed by the fifth percentile of light sensitivity threshold distribution ( Healy MJR et al, Ann Hum Biol 1988;15:17–22). Using this last mathematical function, normal values and 95% CI age–related values were derived. No statistically significant difference was found comparing mean sensitivity of superior vs inferior central hemifield, or nasal vs temporal central hemifield.

Conclusions: : Automatic fundus–related perimetry allows for accurate, repeatable topographic–related examination of retinal threshold of selected retinal areas. Automatic follow–up examination is also available. These data represent the first age–related, normal values database available to clinicians working with fundus–related perimetry. *Microperimetry Study Group: Padova, Ancona, Belluno, Chieti, Genova, Roma Bietti, Roma Oftalmico, Trieste (Depts of Ophthalmology).

Keywords: perimetry • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina 
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