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E.O. Graue, L.U. Gurria, R. Velazquez, J.M. Paulin, A. Haber, C. Santacruz, F. Peniche, A. Gómez, A. Climent, R. Suárez; Indications for Penetrating Keratoplasty in Mexico. 2000–2005 . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5566.
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To examine the leading indications for penetrating keratoplasty in Mexico.
We retrospectively performed a review of clinical records of patients enrolled for penetrating keratoplasty at the Instituto de Oftalmología Fundación Conde de Valenciana from 2000 to 2005. The primary surgical indication was identified
2674 clinical records were reviewed. Mean age was 41 years (range 0.8 –95), males 56.9%, females 43.1%. The leading indication was keratoconus with 37.7%, followed by bullous keratopathy 19.6% , non–specific corneal scaring 7.9%, regraft 5.4% and bacterial keratitis sequelae 4.9%. Although not statistically significant (p = 0.26) we found an increasing trend of bullous keratopathy . Gender differences were present for keratoconus with males exceeding female patients on a 2:1 ratio (p < 0.05). Male exceeded female patients by 3:1 for trauma and congenital anomalies ( p < 0.001). Female exceeded male patients by 1.5:1 for bullous keratopathy, but this was not satistically significant.
To the authors knowledge, this is the first report that identifies the leading indications for penetrating keratoplasty in Mexico. The Instituto de Oftalmología is one of the three tertiary referral centers in the country, thus the results are probably biased. Nevertheless , they were found to be generally in agreement with the data reported in recent literature and they represent the Mexican epidemiological transition in ophthalmology, consequently showing diseases of developing countries such as leucomas secondary to bacterial keratitis, and diseases of developed ones, like bullous keratopathy which is an indirect measure of cataract surgery development in Mexico .
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