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M.Y. Alarbi, T.N. Moutray, G. Mahon, U. Chakravarthy; OCT Characteristics of PDT Treated Choroidal Neovascularisation in Patients With Age Related Macular Degeneration . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5652.
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To examine the relationships between specific baseline OCT characteristics of choroidal neovascularisation in predicting visual outcome in patients undergoing PDT with verteporfin.
Two clinical measures of vision namely distance visual acuity (DVA) and near visual acuity (NVA) were measured using standardised protocols. DVA was recorded as the number of letters read and NVA as the log of the minimum angle. Membranes were classified on OCT as Group 1 (fusiform) or Group 2 (protruding). When mixed these were included in the latter group. Change in each of the measures of vision by OCT subtype was examined by comparison of means.
Maximum change in DVA was seen in the fusiform subtype with a 10 letter improvement compared to 3 letters in group 2. By contrast, improvement in NVA was seen in group 2 (3 line improvement in group 2 versus no change in group 1)
Membrane morphology affects visual outcomes following PDT.
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