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M. Kiyokawa, H. Nakajima, Y. Takizawa, M. Suami, M. Honda, A. Atsushi, M. Tanaka; Measurement Of Volume Of Subretinal Space From Serial C Scan Images Obtained By Oct Ophthalmoscopy . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5712.
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© ARVO (1962-2015); The Authors (2016-present)
Serial C scan images can be obtained by OCT ophthalmoscope from which three dimensional (3D) information of the retina can be constructed. The purpose of this study was to measure the volume of the subretinal space by serial C scan images of the retina.
The topography mode of the OCT Ophthalmoscope (OTI, NIDEK) was used. The recording area was 15x15°, recording time was 2 seconds, and recording depth was 1.5 mm. Within this 2 seconds, 100 serial C scan images were obtained. These images were recorded with a depth interval of about 15 µm, and from these images, B scan images of the retina were constructed. In patients with central serous chorioretinopathy (CSC), we recorded OCT and manually drew the area of subretinal space in the B scan image. The mean height of the subretinal space was measured in several square areas of 0.65x0.65 mm where the subretinal space existed. Then we calculated volume of subretinal space in two patients with CSC.
In one patient, the retinal part of the subretinal space was divided into 16 square of 0.65x0.65 mm. The sum of mean height of these 16 area was 0.484 mm, and the volume of subretinal space was 0.204 (0.484x0.65x0.65) mm3. In the other case, the retinal part was divided into 20 squares and the sum of mean height was 1.17mm and volume was 0.494 (1.17x0.65x0.65) mm3.
These results show that the volume of the subretinal space can be easily calculated from serial C scan images of the retina. This method will allow us to assess and follow the changes in the volume of different parts of the retina.
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