Purchase this article with an account.
J. Kraus, J. Hillenkamp, C. Framme, A. Souka, H. Sachs, V.–P. Gabel; Anatomical And Functional Outcome Of Macular Hole Surgery With And Without Autologous Platelet Concentrate . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5803.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To compare the anatomical and functional outcome of pars–plana–vitrectomy (ppV) with internal limiting membrane (ILM) peeling in macular hole surgery with and without platelet concentrate.
Retrospective analysis of 74 patients with macular hole stage III or IV, who underwent ppV between 2000 and 2004. All patients were operated with indocyanine green assisted ILM–Peeling and gas tamponade. 28 patients (group 1) were operated with platelet concentrate, 46 patients (group 2) without platelet concentrate.
In group 1, the mean best corrected visual acuity (BCVA) improved from preop –0.78 LogMAR (min –1.60/max –0,30) to postop –0,62 LogMAR (min –1,60/max –0,10). In group 2, the mean visual acuity improved from preop –0,99 LogMAR (min –3,00/max –0,40) to postop –0,88 LogMAR (min –1,6/max 0,00). In group 1, 19 patients (67.9%) gained >= 1 line, 10 patients gained more than 3 lines (35.7%). 3 patients remained unchanged, 6 patients (21.4%) lost 1 line. In group 2, 24 patients (52.2%) gained >= 1 line, 13 patients (28.3%) more than 3 lines. 7 patients in this group remained unchanged (15.2%), 15 patients (32.6%) lost visual acuity, 6 patients (13.0%) more than 3 lines. In group 1, the macular hole closure rate was 100%. In group 2, the macular closure rate was 73.9%.
The aid of autologous platelet concentrate appears to improve both the anatomical and the functional outcome of macular hole surgery with ILM–Peeling.
This PDF is available to Subscribers Only