May 2006
Volume 47, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2006
Integrated Neural Photo–Stimulation and Microperimetric Fixation Analysis. Clinical Experience of the Low Vision Research Centre of Milan
Author Affiliations & Notes
  • P.G. Limoli
    Low Vision Research Centre, Milan, Italy
  • E.M. Vingolo
    Ophthalmological Department, La Sapienza University, Roma, Italy
  • L.M. D'Amato
    Low Vision Research Centre, Milan, Italy
  • E. Giacomotti
    Low Vision Research Centre, Milan, Italy
  • R. Solari
    Low Vision Research Centre, Milan, Italy
  • P. Costanzo
    Eye.com, Palermo, Italy
  • A. Ribecca
    Eye.com, Palermo, Italy
  • R. Di Corato
    Low Vision Research Centre, Milan, Italy
  • L. Strocchi
    Low Vision Research Centre, Milan, Italy
  • E. Gilardi
    Low Vision Research Centre, Milan, Italy
  • Footnotes
    Commercial Relationships  P.G. Limoli, None; E.M. Vingolo, None; L.M. D'Amato, None; E. Giacomotti, None; R. Solari, None; P. Costanzo, None; A. Ribecca, None; R. Di Corato, None; L. Strocchi, None; E. Gilardi, None.
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science May 2006, Vol.47, 5835. doi:https://doi.org/
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      P.G. Limoli, E.M. Vingolo, L.M. D'Amato, E. Giacomotti, R. Solari, P. Costanzo, A. Ribecca, R. Di Corato, L. Strocchi, E. Gilardi; Integrated Neural Photo–Stimulation and Microperimetric Fixation Analysis. Clinical Experience of the Low Vision Research Centre of Milan . Invest. Ophthalmol. Vis. Sci. 2006;47(13):5835. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Neural photo–stimulation improves VEPs, Visus and reading coefficient. We have hypothesized that photo–stimulation as the principal mechanism improves the quality of fixation and, in a chain reaction beginning with the foveal detection, all the other visual parameters.

Methods: : In order to do this study we have developed a new method of stimulation called, Integrated Neural Photo–stimulation (INP), which incorporates three methods: I.B.I.S., Visual Pathfinder and Sound Biofeedback. At the beginning and at the end of each cycle we analyse the fixation percentage within foveal two central degrees, BCVA, near visual acuity in pts, VEPs, reading speed and reading coefficient. We examined examples (Group A) composed of 67 eyes. We compared the examples Group A with the variations obtained with the analogous Group B, of 22 eyes, who had previously undergone neural photo–stimulation done only with the Visual Pathfinder. We subsequently compared the increase in the fixation percentage within the two central degrees, the BCVA, for close up done with the integrated neutral photo–stimulation (Group A) and after neural photo–stimulation done only with the Visual Pathfinder (Group B).

Results: : 1) The fixation percentage changes: Group A, from 45,48 (T0) to 69,62% (T1), increase 24,14, percentage change 53,07% (R= 0,00000001 – Dev.St 31,3204). Group B, from 52 (T0) to 66% (T1), increase 14, ( 26,92 %) (R=0,019677 – Dev.St. 33,7648). 2) The BCVA changes: Group A, from 0,31 to 0,39, increase 0,08 ( 25,80%) (R= 0,0000427 – Dev.St. = 0,3004). Group B, from 0,38 to 0,45, increase 0,07 (18,42%)(R= 0,0390938 – Dev.St. 0,3442). 3) The near visual acuity changes: Group A, from 29,27 pts to 24,21 pts, increase 5,06(17,28%) (R= 0,0000074– Dev.St. = 29,0476). Group B, from 22,2 pts to 16,1 pts, increase 6,1(27,47%) (R= 0,0023805 – Dev.St. 16,7108).

Conclusions: : It confirms that the neural photo–stimulation, through a better collimation of fixation within two central degrees, results with an improvement of foveal detection which determines an improvement of visual acuity and reading. This increase can be regulated and improved depending on the photo–stimulative method used. At the moment, we feel that Integrated Neural Photostimulation causes a further increase of the fixation percentage and foveal detection, such it has been analized with microperimetry and can be used successfully during visual rehabilitation.

Keywords: low vision • perception • visual search 
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