May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Comparison of Corneal Endothelium Changes After Trabeculectomy and Deep Sclerectomy
Author Affiliations & Notes
  • S. Arnavielle
    Ophthalmology,
    University Hospital, Dijon, France
  • P.O. Lafontaine
    Ophthalmology,
    University Hospital, Dijon, France
  • S. Bidot
    Ophthalmology,
    University Hospital, Dijon, France
  • A. Guillaubey
    Ophthalmology,
    University Hospital, Dijon, France
  • P. D'Athis
    Biostatistics,
    University Hospital, Dijon, France
  • C. Creuzot–Garcher
    Ophthalmology,
    University Hospital, Dijon, France
  • A.M. Bron
    Ophthalmology,
    University Hospital, Dijon, France
  • Footnotes
    Commercial Relationships  S. Arnavielle, None; P.O. Lafontaine, None; S. Bidot, None; A. Guillaubey, None; P. D'Athis, None; C. Creuzot–Garcher, None; A.M. Bron, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 128. doi:
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      S. Arnavielle, P.O. Lafontaine, S. Bidot, A. Guillaubey, P. D'Athis, C. Creuzot–Garcher, A.M. Bron; Comparison of Corneal Endothelium Changes After Trabeculectomy and Deep Sclerectomy . Invest. Ophthalmol. Vis. Sci. 2005;46(13):128.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Abstract:
 

To compare the effect of trabeculectomy and deep sclerectomy on the corneal endothelium.

 

In a prospective study 62 eyes of 62 patients were included, scheduled for either a single trabeculectomy (n=18), or a single deep sclerectomy (n=14), or a combined trabeculectomy and phacoemulsification (n=11), or a combined deep sclerectomy and phacoemulsification (n=19). Exclusion criteria were history of corneal disease, ocular trauma, inflammation, or previous glaucoma filtering surgery. Preoperative, 3 months and one year postoperative noncontact specular microscopies were performed on central and superior corneas. Endothelial images were interpreted with a computer–assisted analyzer.

 

In central cornea, a statistical significant post operative endothelial cell loss was found after trabeculectomy and deep sclerectomy (alone and combined with cataract extraction) at 3 and 12 months ( p<0.0001). Endothelial cell loss (EC loss) was as follows.

 

 

In upper cornea, the results were similar to central cornea.

 

These findings demonstrate that endothelial cell loss was moderate 3 and 12 months after glaucoma surgery. However, corneal endothelial cell loss was more important after combined surgeries and trabeculectomies suggesting less corneal damage after deep sclerectomy.

 

 
Keywords: cornea: endothelium • cornea: clinical science • anterior segment 
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