May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Preoperative Ocular Massage to Lower the Immediate Intraocular Pressure Spike Following Intravitreal Triamcinolone Acetonide Injection
Author Affiliations & Notes
  • J. Lee
    Ophthalmology, Hanyang university Hospital, Seoul, Republic of Korea
  • J.H. Hwang
    Ophthalmology, Hanyang University Hospital, Seoul, Republic of Korea
  • Y.S. Park
    Ophthalmology, Hanyang University Hospital, Seoul, Republic of Korea
  • Y.J. Lee
    Ophthalmology, Hanyang University Hospital, Seoul, Republic of Korea
  • B.R. Lee
    Ophthalmology, Hanyang University Hospital, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  J. Lee, None; J.H. Hwang, None; Y.S. Park, None; Y.J. Lee, None; B.R. Lee, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 1454. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      J. Lee, J.H. Hwang, Y.S. Park, Y.J. Lee, B.R. Lee; Preoperative Ocular Massage to Lower the Immediate Intraocular Pressure Spike Following Intravitreal Triamcinolone Acetonide Injection . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1454.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: The immediate intraocular pressure(IOP) spike induced by intravitreal volume loading may insult the eyes vulnerable to ischemic change. In present study, we evaluated the effect of preoperative ocular massage to lower the immediate IOP spike following intravitreal triamcinolone acetonide injection(IVTA). Methods:This prospective non–randomized comparative case–series study comprised thirty eyes of 27 patients with macular edema due to diabetic retinopathy and retinal vein occlusion. Seventeen eyes of 15 patients underwent IVTA(4mg/0.1ml) with ocular massage(preoperative, digital, intermittent for 5 minutes)(group A), and thirteen eyes of 12 patients underwent IVTA without ocular massage(group B). Paracentesis was not performed in any of the eyes. The IOPs before and after massage, and the IOPs after IVTA(immediately, 10minutes, 20minutes, 30minutes, and 2 hours after IVTA) were measured, respectively. In addition, the presence and duration of pulsation of central retinal artery was checked by indirect ophthalmoscopy. Exclusion criteria included preoperative ocular hypertension, glaucoma, pseudophakia and the presence of vitreous leakage during IVTA. Results:Mean preoperative decrease in IOP induced by ocular massage was 6.54±3.05 mmHg. Mean IOP immediately after IVTA was 29.0 ± 10.79 mmHg in group A and 38.12 ± 12.32 mmHg in group B, respectively. Mean IOP at 10 minutes after IVTA was 23.02 ± 7.82 mmHg in group A and 32.13 ± 9.24 mmHg in group B, respectively. Statistically, the IOP increment of group A is significantly lower than that of group B immediately and at 10 minutes after IVTA(p=0.03, p=0.04, Independent t–test). Mean IOPs at 20 minutes, 30 minutes and 2 hours after IVTA were not significantly different between group A and group B(p=0.31, p=0.19, p=0.24, Independent t–test). Immediately after IVTA, three eyes(25%) out of twelve eyes which were not obscured by triamcinolone particles in group A and five eyes(62.5%) out of nine eyes in group B demonstrated pulsation of the central retinal artery. 5 minutes after IVTA, none demonstrated pulsation of the central retinal artery any longer. Conclusions: Even a short span of the immediate IOP spike following IVTA may not be tolerable. Ocular massage is easy and simple to perform, inducing a significant decrease in IOP. This preoperative hypotension by ocular massage is effective in diminishing the immediate IOP spike following IVTA.

Keywords: drug toxicity/drug effects • injection • intraocular pressure 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×