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K. Hellgren, J. Ygge, L. Jacobson, A. Hellström, O. Flodmark, L. Martin; Visual Function in 15 Years–Old Subjects With Very Low Birth Weight – A Population–Based Study . Invest. Ophthalmol. Vis. Sci. 2005;46(13):1925.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To study visual function and perception together with the brain morphology with MRI in 15 years–old subjects with very low birth weight (≤ 1500 g; VLBW) compared to age–matched controls. Methods: Fifty–nine 15–years–old subjects (33 males and 26 females) with VLBW and 55 age–matched controls (population–based) underwent examinations including visual acuity (VA), stereo acuity (TNO test) and estimation of refraction in cycloplegia. Computerized perimetry was performed with Rarebit Microdot perimetry (RB). All subjects answered a questionnaire together with their parents, concerning former and remaining visual and/or perceptual problems. In addition, all the VLBW subjects underwent MRI of the brain. Results: Compared to the controls, the VLBW subjects had significantly lower binocular VA, reduced stereo acuity, larger refractive errors and a significant sensitivity decrease in RB perimetry. In the questionnaire they also reported significantly more problems concerning reading, depth and movement perception and simultaneous capacity compared to the control group. Thirty–two percent of the VLBW subjects had pathological MRI findings from which 7% had severe abnormalities. All subjects with binocular VA < 20/20 had abnormal MRI findings and all subjects with severe MRI abnormalities showed subnormal visual function and perception. Conclusions: The frequency of pathological MRI findings in the VLBW group was in concordance with previous studies. The questionnaire revealed subjective visual and perceptual problems that did not fully correlate with the shown visual dysfunction. Hence, the questionnaire seemed to be the best way to reveal every day problems in VLBW subjects.
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