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W. Rahman, F. Proudlock, I. Gottlob; Oral Gabapentin Treatment for Symptomatic Heimann–Bielschowsky Phenomenon . Invest. Ophthalmol. Vis. Sci. 2005;46(13):2941.
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Purpose: To describe a patient with symptomatic Heimann–Bielschowsky phenomenon (HBP) treated successfully with oral gabapentin Methods: A 57 year old patient with retinitis pigmentosa had a twelve month history of vertical oscillopsia. The right visual acuity was 6/60 and the left visual acuity was 6/18 with glasses. He had a coarse, slow, pendular, vertical movement of the right eye for distance and near fixation. The clinical picture was of Heimann–Bielschowsky phenomenon. He was commenced on oral gabapentin with gradual increase in dose to 2400mg per day. Eye movement recordings were performed with an infrared pupil tracker (EyeLink I, 250 Hz) before and after treatment. Results:The patient became significantly less symptomatic on gabapentin. The right visual acuity improved to 6/24 with glasses. Eye movement recordings confirmed markedly reduced vertical oscillations of the right eye. The patient continues on gabapentin with no side effects and sustained effect. Conclusions: The vertical nystagmoid movement in HBP can be significantly reduced and symptoms significantly improved when treated with oral gabapentin.
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