May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Macular Dislocation and Strabismus in a Preterm Population With and Without ROP
Author Affiliations & Notes
  • R. De Santis
    Ophthalmology, Catholic University, Rome, Italy
  • D. Lepore
    Ophthalmology, Catholic University, Rome, Italy
  • G. Savino
    Ophthalmology, Catholic University, Rome, Italy
  • F. Molle
    Ophthalmology, Catholic University, Rome, Italy
  • M.M. Pagliara
    Ophthalmology, Catholic University, Rome, Italy
  • M.T. Rebecchi
    Ophthalmology, Catholic University, Rome, Italy
  • M. Bruno
    Ophthalmology, Catholic University, Rome, Italy
  • E. Balestrazzi
    Ophthalmology, Catholic University, Rome, Italy
  • Footnotes
    Commercial Relationships  R. De Santis, None; D. Lepore, None; G. Savino, None; F. Molle, None; M.M. Pagliara, None; M.T. Rebecchi, None; M. Bruno, None; E. Balestrazzi, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 4112. doi:
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      R. De Santis, D. Lepore, G. Savino, F. Molle, M.M. Pagliara, M.T. Rebecchi, M. Bruno, E. Balestrazzi; Macular Dislocation and Strabismus in a Preterm Population With and Without ROP . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4112.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To evaluate prevalence of macular dislocation and strabismus in a preterm population. Materials and Methods: 554 preterm children (BW less than 1251gr and/or GA ≤32 weeks) born from Jan ‘98 to Dec ’02 were screened for ROP at the Catholic University Hospital NICU in Rome. The mean BW was 1273,87gr (range 350–2750gr) and the mean GA was 29,58 weeks (range 23–35w). Ten babies died inside the NICU. ROP was diagnosed in 184 infants with a mean BW 910,7 grams (range 350–1530) and mean GA 27,7 (range 23–35w). 5,31% of all preterm infants (15,8% of all ROP) reached threshold and were treated with cryo (before ’99) or laser: six of them died during the first year of life. A follow–up program for preterms was set based on orthoptic, fundus and anterior segment examination, cycloplegic refraction (using an automated refractometer) Results: we collect data from 316 babies (57%) with a minimum of 1 year follow–up. 28% of the entire population were eso or exotropic at 5 year of the corrected age, with higher prevalence of strabismus in more severe and posterior ROP. Macular heterotopia, ranging form slight dislocation to severe dragging, was found in 2% all preterm at 5 years of age. Resulting pseudoesotropia was more consistent in pre–threshold ROP (76,9%) than in threshold ROP (23,07%). Conclusions: surgical ablation of avascular retina seems to improve structural and functional outcome of ROP. Data from a long term follow up will allow to evaluate therapeutic options of this form of pseudostrabismus.

Keywords: retinopathy of prematurity • macula/fovea • strabismus 
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