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M. Zanotele, F.B. Aggio, N.S. B. Moraes, R.A. Costa, M.E. Farah; Central Serous Chorioretinopathy: A Study By Stratustm Optical Coherence Tomography . Invest. Ophthalmol. Vis. Sci. 2004;45(13):534.
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Purpose: To evaluate the morphology of central serous chorioretinopathy using STRATUSTM imaging system and to correlate its findings with those of biomicroscopy and fluorescein angiography (FA). Methods: 25 consecutive eyes of 21 patients (18 men, three women; mean age ± SD, 40.3 ± 8.5; range, 24 to 67 years) with central serous chorioretinopathy were examined with STRATUSTM optical coherence tomography (STRATUSOCTTM) during the acute phase and for 1 to 6 months thereafter (mean, 2.6 ± 1.8 months). Results: In the acute phase, focal thickening or detachment of the retinal pigment epithelium (RPE) was detected in 7 (28%) eyes by fundus biomicroscopy, 5 eyes by FA and 18 (72%) eyes by STRATUSOCTTM. Out of 43 leakage points identified in the successive fluorescein angiography examinations, 27 (63%) corresponded to serous RPE detachments or focal thickenings of the RPE on STRATUSOCTTM images. STRATUSOCTTM showed foveal neurosensory retina detachment in 21 (84%) eyes, as well as loss, distortion and normal appearance of the physiologic foveal pit in 15 (60%), 4 (16%) and 6 (24%) eyes, respectively. Evidence of outer retinal layers impairment was detected in 6 (24%) eyes. In one patient, signs of loss of continuity in the RPE and outer retinal layers at the border of a RPE detachment were noted. STRATUSOCTTM follow–up examinations disclosed gradual diminution of subretinal fluid in 12 (48%) eyes, unchanged picture in 6 (24%) eyes and worsening in 4 (16%) eyes, with additional evidence of outer retinal layers injury, such as edema and increased optical reflectivity. Three eyes were lost from the study. Conclusions: Fundus biomicroscopy as well as FA failed to demonstrate subclinical pathologic changes, such as signs of outer retinal layer injury and loss of continuity in the RPE. STRATUSOCTTM is a noninvasive useful tool that provides valuable information on the morphology of central serous chorioretinopathy.
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