May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Accomodative amplitude in eyes implanted with Crystalens AT45 and 1Cu IOLs. Prospective, randomized, controlled, 12–month clinical trial.
Author Affiliations & Notes
  • G. Marchini
    Ophthalmology, Univ Verona, Verona, Italy
  • R. Tosi
    Ophthalmology, Univ Verona, Verona, Italy
  • P. Mora
    Ophthalmology, Univ Parma, Parma, Italy
  • E. Pedrotti
    Ophthalmology, Univ Verona, Verona, Italy
  • F. Manzotti
    Ophthalmology, Univ Parma, Parma, Italy
  • P. Sartori
    Ophthalmology, Univ Verona, Verona, Italy
  • S.A. Gandolfi
    Ophthalmology, Univ Parma, Parma, Italy
  • Footnotes
    Commercial Relationships  G. Marchini, None; R. Tosi, None; P. Mora, None; E. Pedrotti, None; F. Manzotti, None; P. Sartori, None; S.A. Gandolfi, None.
  • Footnotes
    Support  FIL2002, Univ. Parma
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 1729. doi:
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      G. Marchini, R. Tosi, P. Mora, E. Pedrotti, F. Manzotti, P. Sartori, S.A. Gandolfi; Accomodative amplitude in eyes implanted with Crystalens AT45 and 1Cu IOLs. Prospective, randomized, controlled, 12–month clinical trial. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):1729.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: (a) to measure the post–operative accomodative amplitude in eyes implanted with "accomodative" IOLs (b) to explore anterior segment changes upon IOL implantation Methods: Study design: prospective, randomized, controlled clinical trial, 12 month . Population: 41 patients (59 eyes), scheduled for cataract surgery (clear cornea phacoemulsification in local anaesthesia, two surgeons, GM and SAG) , agreed to participate in the study. In 26 eyes (17 patients) an AT45 IOL was implanted. 25 eyes (16 patients) were scheduled for a 1CU IOL, 8 eyes (8 patients) were scheduled for a non–accomodative acrylic foldable IOL.. Age : 45–65 years. Pre–operative best corrected visual acuity: 20/63 – 20/32. Study procedures: (a) accomodation measured by adding a negative sphere to the far–distance correction until 4/5 letters of the smallest detectable line were properly identified. (b) anterior chamber depth (i.e. the distance between the posterior endothelium and the anterior optic of the IOL ) and the amplitude of the scleral–ciliary process angle were measured by UBM in an accomodation–solicited condition and in a relaxation state. The measurements were made on the individual UBM images by two "masked" independent observers (RT and PM Results: Post–operative uncorrected far distance visual acuity ranged between 20/25 and 20/16. The 12–month data on accomodation, and on the decrease of (a) the AC depth and (b) the sclero–ciliary angle, upon solicited accomodation, are summarized in the table: 

The accomodative amplitude was greater upon implantation of 1CU IOL (p = 0.0019 vs non–accomodative IOL, p = 0.00002 vs AT45, power = 85%, alpha probability = 10%). Conclusions: (a) a measurable accomodation was observed in eyes implanted with non–accomodative IOLs, (b) the accomodative amplitude was greater in eyes implanted with 1CU IOLs. (c) in our cohort of eyes, the average accomodation offered by "accomodative" IOLs was < 1 diopter. (d) further studies are needed to clarify which eye(s) can be the best candidate for an implantation with accomodative IOLs

Keywords: cataract • visual acuity • ciliary muscle 
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