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J.–C. Pinelli, J. Conrath, B. Ridings; ICG and Fluorescein angiography in posterior scleral reinforcement in rabbits . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2387.
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Purpose: To study the effects on retinal and choroidal circulations in rabbits after 5 months of posterior scleral reinforcement with bands of PTFE in deprivation myopia. Methods: Twelve 22–day–old pigmented rabbits were randomly distributed into three groups: In the first group (n=4), we performed an eyelid suture on one eye of each animal to induce deprivation myopia. In the second group (n=4), one eye of each animal was implanted with a posterior scleral reinforcement band made of PTFE. In the third group (n=4), we associated on the same eye, posterior scleral reinforcement and eyelid suture. The controlateral eye of each animal was a control eye. The eyes of nine rabbits were examined by fluorescein and indocyanine green angiography after five months from baseline. Results: In 8 of 9 cases the angiograms showed normal choroidal circulation. However,we observed in one rabbit of group 2 several polypidal vascular choroidal formations at the level of the band. We hypothesize the development of choroidal neovascularization by a compression mechanism. Conclusions: In this study, posterior scleral reinforcement is well tolerated at the level of retinal and choroidal circulations in rabbits. It is necessary to respect certain rules and notably, the absence of scleral indentation by the band.
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