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A. Suarez–Licona, L. Arellanes–Garcia, M. Ruiz–Cruz, C. Recillas–Gispert; Long Term Complications And Functional Evolution Of Visual Acuity In Vogt Koyanagi Harada Disease Patients. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2696.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: Determine long term evolution in VKH patients. Methods: Patients without active inflammation underwent detailed ophthalmologic evaluation. Fluorescein angiogram (FA), standard and multifocal electroretinogram (ERG), color and contrast sensitivity test and Humphrey automated perimetry (HAP) were performed. Results: 128 patients were contacted by phone, 19 (38 eyes) underwent full evaluation. Mean age was 38 years; mean follow up was 56.31 months. Dallen–Fuchs–Like spots and sunset glow fundus were seen in 76.31% of eyes. Spotted hyperfluorescence was noticed in 81.57 % of cases. HAP showed a decreased sensitivity in 20.58% of eyes. Color test reported disturbance in 45.94% eyes. Contrast sensitivity test showed alteration in 78.37% eyes. Multifocal electroretinogram showed abnormal signal responses in all the eyes studied. Of the 38 eyes, 44.73% had surgery and 64.70% of these had glaucoma surgery. Conclusions: Our study report alterations in macular sensitivity in all eyes. ERG showed a generalized alteration of the retina. Contrast sensitivity test is affected more frequently than color test. Severe depression in multifocal ERG has an important relation with final visual acuity. The presence of glaucoma is an important factor that determines a poor visual acuity.
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