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T. Furuya, A. Kozaki, Y. Ishii, T. Maeda, Y. Inoue; T2 relaxation time as a marker for the improvement of thyroid associated ophthalmopathy after radiotherapy . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2718.
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Purpose: T2 relaxation time (T2T) in MRI is prolonged in the edematous tissue. We evaluated the efficacy of radiotherapy for thyroid associated ophthalmopathy (TAO) using T2T. Methods: Thirty patients with TAO underwent liniac therapy (15 Gy in total). None received steroid therapy during the observation period. Twenty cases had thickening of the extraocular muscle and ten had no particular changes before radiation. T2T of the right medial rectus muscle was repeatedly measured at 1,3,6 and 12 months after radiotherapy using Phillips T–10–NT. We evaluated the maximum, minimum, mean and standard deviation (SD) of T2T from a maximum plane of the medial rectus muscle in the coronal slice of MRI images. Results: An objective evaluation for the edematous extraocular muscle was made possible by MRI. The maximum, mean (Figure) and SD of T2T were clearly shortened after radiotherapy in the thickened muscle group. However, there were no changes in the normal muscle group. Conclusion: T2 relaxation time can be a marker for the improvement of TAO after radiotherapy. View OriginalDownload SlideView OriginalDownload Slide
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