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R.A. Juarez, F. Manns, R.W. Knighton, S.R. Uhlhorn, J.M. Parel; Optical And Physical Model For Retinal Imaging In The Mouse. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2788.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To construct an optical and physical model of the mouse eye for the development of mouse retinal imaging systems. Methods: A reduced paraxial optical model of the mouse eye was developed using biometric and optical measurements published by Remtulla et al. (Vision Res.1985; 25,21–31), and Tejedor et al. (Ophthalmol Vis Sci. 2003;44:32–36). The reduced model was used to calculate entrance/exit pupil, retinal field of view, retinal image height, and develop a physical model that simulates the paraxial imaging system of the mouse. Results: The parameters of the reduced paraxial model are the following (all distances are given with respect to the anterior corneal surface): position of nodal point 1.548mm; position of entrance pupil 0.448mm; position of image focal plane 3.632mm; position of exit pupil –0.044mm. The entrance pupil magnification is 1.098 and the exit pupil magnification is 1.435 with a 2mm diameter mouse dilated pupil. The retinal full field of view is 88 degrees. The physical model consists of a 3mm diameter LaSFN9 plano convex lens with a refractive index of 1.850, and a focal length of 3mm, and a 3.83 mm long PMMA cylinder directly glued to the back surface of the lens. Conclusion: The study demonstrates the feasibility of building a physical model of the mouse eye using standard optical components. CR: None Support: We acknowledge the generosity of the Wollowick Family Foundation and Mrs. Patricia Wollowick for their support; the Florida Lions Eye Bank; Research to Prevent Blindness, NY, NY; The Henri and Flore Lesieur Foundation.
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