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G.T. Smith, L.F. Smith, J.D. Stevens; Randomised Prospective Double Masked Study of Wavefront–Guided LASIK Treatment to One Eye and Non–Wavefront Guided Treatment to the Contralateral Eye . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2822.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To compare wavefront guided primary LASIK with treatment based on manifest refraction for compound myopic astigmatism. Patients & Methods: Patients interested in LASIK refractive surgery were recruited. The eyes had to be within 1.0D spherical equivalent, with less than 2dc astigmatism and 6/6 or better corrected acuity in each eye. Mesometer night vision testing, LogMAR acuity, Pelli–Robson contrast testing, wavefront scanning and refractive assessment were performed at each visit pre and post–operatively. Results: There are 9 eyes in each group. Prior to LASIK the wavefront higher order aberration score was 0.27rms wavefront error (normalised) in each group. Three months after treatment the higher order aberration mean score was 0.42 in the non–wavefront treated group and 0.28 in the wavefront treated group. The non–wavefront treated group had an overall rise in higher order aberrations following surgery. The mean spherical equivalent (± standard deviation) at 3 months post–op was 0.1 ± 0.40D in the non–wavefront group and 0.0 ± 0.34D in the wavefront–treated group. Night vision data, contrast sensitivity and subjective comparative vision will be presented. Conclusions: Primary wavefront guided LASIK using the VISX StarS4 laser system in this randomised study demonstrates better metrics for the wavefront arm of the trial than the non–wavefront treated eyes.
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