May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Prevalence of age related maculopathy in Northern India
Author Affiliations & Notes
  • U. Chakravarthy
    Ophthalmology, Queens Univ&Royal Victoria Hos, Belfast, United Kingdom
  • G. Murthy
    Epidemiology, RP Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • S. Gupta
    Epidemiology, Dr RP Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  • G. Price
    Epidemiology and Aging Studies, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • M. Dherani
    Epidemiology and Aging Studies, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • N. Morrison
    Ophthalmology, Queen's University, Belfast, United Kingdom
  • A. Fletcher
    Epidemiology and Aging Studies, London School of Hygiene and Tropical Medicine, London, United Kingdom
  • Footnotes
    Commercial Relationships  U. Chakravarthy, None; G. Murthy, None; S. Gupta, None; G. Price, None; M. Dherani, None; N. Morrison, None; A. Fletcher, None.
  • Footnotes
    Support  Wellcome Trust UK (G 066082)
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 3059. doi:
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      U. Chakravarthy, G. Murthy, S. Gupta, G. Price, M. Dherani, N. Morrison, A. Fletcher; Prevalence of age related maculopathy in Northern India . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3059.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose:To obtain estimates of the prevalence of age –related maculopathy in the Indian setting. Methods: 1443 people (median age 60 years), 52% women, were identified from enumeration of the 50+ age group in 11 randomly sampled villages from a peri–urban district of Haryana, Northern India. 87 % attended for examination. Using a digital fundus camera, two non–simultaneous 350 stereoscopic colour images were acquired for each eye, and sent to the digital fundus photograph reading centre, at Queen’s University of Belfast, Northern Ireland for grading using the International ARM Epidemiological Study Group classification. The results presented here are based on grade in the worst eye Results:Fundus images were obtained for 1101 of 1255 participants. 8.4% of these could not be graded due to dense opacification of the lens. 33.9%, 95% CI (26.6,42.0) had signs of early ARM Grade 1 (drusen or pigmentary abnormalities only). Late stage AMD was present in 1.4 % (95% CI 0.8,2.3) overall and in 4.6% ( 2.7, 7.8%) of those aged 70+. 93% of AMD was neovascular. These figures are likely to be an underestimate as those with ungradeable photographs due to cataract might also be expected to have a higher prevalence of ARM. Conclusions: These results show that early stages of ARM are more prevalent than in comparable age groups in western populations while the results for AMD suggest a prevalence of at least equivalent.

Keywords: age–related macular degeneration • clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology • clinical (human) or epidemiologic studies: prevalence/incidence 
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