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A. Oguido, A.M. B. Casella, T. Matsuo, R.M. A. Silva, E.H. F. F. Ramos, D. Hasegawa, R.F. Berbel; AGE–RELATED MACULAR DEGENERATION PREVALENCE IN A JAPANESE–BRAZILIAN POPULATION . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3130.
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Purpose: : The aim of this study was to determine the prevalence of age–related maculopathy lesions (ARM), a degenerative disease of the retina and the leading cause of irreversible blindness and visual impairment, in an elderly Japanese–Brazilian population, living in Londrina, Paraná – Brazil Methods: : Population–based cross–sectional study. Methods: A group of 478 subjects (79.7%), from a total of 600 registered members of the local Japanese association, aging at least 60 years old, were ophthalmologically examined. The presence of ARM in the early stage (defined by the presence of drusen > 63µm and pigmentary abnormalities) and also the presence of ARM in the late stages (defined by the presence of geographic atrophy or exudative maculopathy) were determined by grading from fundus examination by indirect ophthalmoscope, slit lamp, and colour fundus photographs Results: The mean age of the examined subjects was 71 years old, 47% males and 63% females. The overall prevalence of ARM was 15.1% (confidence interval [CI] 95%: 12–18.7). It was observed that the frequency and severity of ARM increases with age (p=0.001). There was no significant difference in the prevalence of ARM between males or females (p=0.171), but males presented higher risk to develop the early and late ARM lesions than females among 80s (OR: male=3.33 and female=1.98). The prevalence of early ARM features was 13.4% (CI 95%: 10.7–17.1), and increased with age (p=0.028). Geographic atrophy was present in 0,8% and neovascular age reated macular degeneration in 0,8%. Conclusions: This Japanese–Brazilians population has shown a similar prevalence of early and late stages ARM and its component lesions compared to Western countries. However, it was more prevalent than in Japanese studies. These higher rates will continue to increase the importance of ARM as our population gets older and more studies are necessary to identify risk factors and prevention methods.
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