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H. Oh, B.–Y. Ahn, S. Kim, S. Lee, O. Kwon; Two Year Experience of Photodynamic Therapy of Age–Related Macular Degeneration in Korea . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3148.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose:To determine if photodynamic therapy(PDT) with verteporfin can safely reduce the risk of vision loss in patients with subfoveal choroidal neovascularization(CNV) caused by age–related macular degeneration(AMD) in Korea. Methods:We reviewed 67 cases of CNV due to ARMD who was treated by PDT retrospectively. The visual acuity was measured by modified ETDRS chart before and the after treatment. Color and red–free fundus photographs, fluorescein angiography, and indocyanine green angiography were performed and evaluated for lesion character and leakage at every follow–up. Results:Eighty eight percent of patients have occult CNV. Mean visual acuity was 20 letters and mean greatest linear dimension was 3181um. Visual acuity was improved or preserved in 75% after 2–year follow–up. In fluorescein angiography, leakage was increased in 13.1% at 2–year follow–up. Conclusions:The PDT is safe and effective way of treatment for subfoveal CNV caused by AMD.
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